Peer Reviewed Research Papers
2024
Wood TWP, Henriques WS, Cullen HB, Romero M, Blengini CS, Sarathy S, Sorkin J, Bekele H, Jin C, Kim S, Chemiakine A, Khondker R, Isola JVV, Stout MB, Gennarino VA, Mogessie B, Jain D, Schindler K, Suh Y, Wiedenheft B, Berchowitz LE. Two retrotransposon-derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity. bioRxiv. 2024-05.
Tang S., Conte V., Zhang DJ, Žedaveinytė R, Lampe GD, Wiegand T, Tang LC, Wang M, Walker MWG, George JT, Berchowitz LE, Jovanovic M, Sternberg, S. H. (2024). De novo gene synthesis by an antiviral reverse transcriptase. Science. 2024. doi: 10.1126/science.adq0876
2023
Gaspary A, Laureau R, Dyatel A, Dursuk G, Berchowitz LE. Rie1 and Sgn1 form an RNA-binding complex that enforces the meiotic entry cell fate decision. Journal of Cell Biology. 2023. 222(111).
Ottoz DSM, Tang L, Jovanovic M, Dyatel A, Berchowitz LE. Assembly and function of the amyloid-like translational repressor Rim4 is coupled with nutrient conditions. EMBO Journal. 2023. e113332.
Leeman-Neill R, Song D, Bizarro J, Wacheul L, Rothschild G, Singh S, Yang Y, Sarode A, Gollapalli K, Wu L, Zhang W, Chen Y, Lauring M, Whisenant DE, Bhavsar S, Lim J, Swerdlow S, Bhagat G, Zhao Q, Berchowitz LE, Lafontaine D, Wang J, Basu U. Non-coding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression. Nature Genetics. 2023. 1-15.
2022
Clearance of an amyloid-like translational repressor is governed by 14-3-3 proteins.Herod SG, Dyatel A, Hodapp S, Jovanovic M, Berchowitz LE. Cell Reports. 2022. May 3;39(5):110753.
Pal I, Grilo AS, Gaspary A, Sharma SD, Scotto L, O'Connor OA, Jovanovic M, Changchun D, Berchowitz LE. Inhibition of Casein Kinase 1 Delta Disrupts Translation Initiation and Exerts Potent Anti-Lymphoma Activity. Blood Advances. 2022 May 25
Identification of 14-3-3 proteins, Polo kinase, and RNA-binding protein Pes4 as key regulators of meiotic commitment in budding yeast. Gavade JN, Puccia CM, Herod SG, Trinidad JC, Berchowitz LE, & Lacefield S. Current Biology. 2022. 32(7), 1534-1547
The cAMP signaling pathway regulates heterochromatin assembly. Bao K, Shan C-M, Chen X, Raiymbek G, Munroe J, Koutmou K, Ragunathan K, Lu C, Berchowitz LE, and Jia S. PLoS Genetics. 2022. 18(2)
2021
Meiotic cells counteract programmed retrotransposon activation via RNA-binding translational repressor assemblies. Laureau R, Dyatel A, Dursuk G, Brown S, Adeoye H, Yue J-X, De Chiara M, Harris A, Ünal E, Liti G, Adams IR, Berchowitz LE. Developmental Cell. 2021. 56(1), 22-35
Fusobacterium nucleatum secretes amyloid-like FadA to enhance pathogenicity. Meng Q, Gao Q, Mehrazarin S, Tangwanichgapong K, Wang Y, Huang Y, Pan Y, Robinson S, Liu Z, Zangiabadi A, Lux R, Papapanou PN, Guo XE, Wang H, Berchowitz LE*, Han YW*. EMBO Reports. 2021. e52891. *co-corresponding
2019
Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability. Bryant EE, Sunjevaric I, Berchowitz LE, Rothstein RR and Reid RJD. Nucleic Acids Research. 2019. 47(17), 9144-9159
Developmental regulation of an organelle tether coordinates mitochondrial remodeling in meiosis. Sawyer EM, Joshi PR, Jorgensen V, Yunus J, Berchowitz LE, & Ünal E. Journal of Cell Biology. 2019. 218(2): 559-579
Granules bearing translation factor mRNAs direct the protein synthetic machinery to regions of polarized growth. Pizzinga M, Bates C, Lui J, Forte G, Linney E, Morales F, Knotkova B, Wilson B, Solari CA, Berchowitz LE, Portela P, Ashe, MP. Journal of Cell Biology. 2019. 218(5), 1564-1581
2018
Carptenter K, Bell RB, Yunus J, Amon A, Berchowitz LE. Phosphorylation-Mediated Clearance of Amyloid-like Assemblies in Meiosis. Developmental Cell. 2018. 45(3). p392–405
Phizicky DV, Berchowitz LE, Bell SP. Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis. eLife. 2018. Feb 1;7:e33309.
Editorial and Review
The role of disorder in RNA binding affinity and specificity. Ottoz DSM, and Berchowitz LE. Open Biology. 10.12. 2020. 200328
Induced pluripotent stem cells as a tool for comparative physiology: lessons from the thirteen-lined ground squirrel. Ou J, Rosa S, Berchowitz LE, Li, W. Journal of Experimental Biology. 2019. 222 (19), jeb196493